Effect of 6-mercaptopurine (6-mp) on Different Classes of Antibody
نویسندگان
چکیده
In the primary response of mice and rabbits immunized with foreign red cells, 6-MP administration prolonged the formation of 19S antibody. 7S antibody formation was delayed and reduced in these animals. Animals treated with 6-MP during primary response exhibited a preferential 19S response when challenged in the anamnestic response. Animals immunized with small doses of antigen and treated with 6-MP only during the secondary response, reversed the usual antibody pattern and responded with preferential 19S antibody formation.
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 122 شماره
صفحات -
تاریخ انتشار 1965